现代病例候选

Successful Administration of Kampo Medicine and Acupuncture Treatment to Improve Erythromelalgia: A Case Report.

Successful Administration of Kampo Medicine and Acupuncture Treatment to Improve Erythromelalgia: A Case Report.

Erythromelalgia is a rare disease characterized by a triad of recurrent burning pain, redness with pain, and hot flashes in the legs during attacks. We report the case of a 40-year-old woman who suffered from refractory erythromelalgia for 15 years and was successfully managed with Kampo medicine and acupuncture. Her pain was refractory to seven types of oral medications and intravenous lidocaine injections. Byakkokaninjinto was also administered for concomitant polydipsia in addition to acupuncture, unseiin, orengedokuto, and sokeikakketsuto. Because erythromelalgia has no established treatment, traditional Kampo medicine combined with acupuncture may help improve the quality of life of affected patients.

Intractable Recurrent Abscess Around the Nipple Caused by Mastitis Remitted by Kampo Medicine Treatment: A Case Report.

Intractable Recurrent Abscess Around the Nipple Caused by Mastitis Remitted by Kampo Medicine Treatment: A Case Report.

We present a case of a 46-year-old woman with recurrent breast abscess resistant to conventional treatments. Initial diagnosis of mastitis led to antibiotic therapy; however, abscess formation recurred. Subsequent interventions, including incision, drainage, and various antibiotics, were insufficient because of recurrent infections. Due to the side effects of long-term antibiotic use, the patient was referred to the Kampo medicine department to address the premenstrual symptoms and recurrent infections. Treatment with Kampo medicines resulted in significant symptom reduction within a month. After treatment, the patient experienced mild symptoms, and breast abscess recurrence was prevented for more than two years. This case highlights the potential role of Kampo medicine in the management of refractory breast abscesses associated with premenstrual symptoms. Further research is required to explore the efficacy and mechanisms of action of Kampo medicines in similar cases.

A Case Report of Pheochromocytoma Presenting With a Tongue Sign Indicative of Blood Deficiency.

A Case Report of Pheochromocytoma Presenting With a Tongue Sign Indicative of Blood Deficiency.

Pheochromocytoma is a rare neuroendocrine tumor presenting with varied clinical symptoms. We present a unique case of pheochromocytoma in a 46-year-old male who developed paroxysmal palpitations, headaches, and elevated blood pressure. Notably, his tongue showed atypical signs of blood deficiency (pale white, thin, and emaciated appearance), which we attributed to peripheral vasoconstriction from sympathetic hyperactivity. His pulse and abdominal findings aligned with qi counterflow in Kampo medicine (traditional Japanese herbal medicine). Despite treatment with Saikokaryukotsuboreito, a traditional herbal formula prescribed to address qi counterflow, only partial improvement of neuropsychiatric symptoms was observed. Further evaluation by an endocrinology specialist confirmed the diagnosis of pheochromocytoma through advanced diagnostic modalities, including scintigraphy. Pheochromocytoma is known to induce sympathetic hyperactivity via excessive catecholamine production, resulting in peripheral vasoconstriction and compromised blood flow, particularly in distal areas such as the tongue.  This case illustrates that sympathetic hyperactivity can produce tongue signs mimicking blood deficiency patterns. Recognition of this discrepancy between tongue signs and other clinical findings prompted further investigation, leading to the diagnosis of pheochromocytoma through modern diagnostic methods. Our experience demonstrates how the integration of Kampo and Western diagnostic approaches enables accurate diagnosis of underlying conditions.

Remission Induced by Shichimotsukokato in an Older Adult With Nephrotic Syndrome Secondary to Diabetic Kidney Disease: A Case Report.

Remission Induced by Shichimotsukokato in an Older Adult With Nephrotic Syndrome Secondary to Diabetic Kidney Disease: A Case Report.

Nephrotic syndrome is a major renal disease characterized by massive proteinuria, hypoalbuminemia, systemic edema, and hyperlipidemia. Diabetic kidney disease (DKD) can induce secondary nephrotic syndrome, which is often challenging to manage with conventional treatments such as renin-angiotensin system inhibitors and diuretics. We present a case of a 90-year-old woman with DKD who developed nephrotic syndrome secondary to DKD that was refractory to standard treatments. Upon administration of shichimotsukokato (SCMKT), a representative Kampo formula created in Japan, there was a marked reduction in the proteinuria and an improvement in the serum albumin concentration, leading to remission of the nephrotic syndrome and enabling tapering of the renin-angiotensin system inhibitor and diuretics. This case suggests that SCMKT may be a candidate therapeutic option for nephrotic syndrome in patients with DKD. Further studies are needed to clarify the clinical benefits and pharmacological mechanisms of SCMKT in DKD.

Korean medicine combination treatment for chronic tinnitus unresponsive to conventional treatment: A case report and review of literature.

Korean medicine combination treatment for chronic tinnitus unresponsive to conventional treatment: A case report and review of literature.

Long-term integrative personalized medicine care in end-stage renal disease and stroke: A CARE-compliant case report.

Long-term integrative personalized medicine care in end-stage renal disease and stroke: A CARE-compliant case report.

Rationale: End-stage renal disease (ESRD) is characterized by severely impaired renal function that necessitates dialysis or kidney transplantation for patient survival. Integrative Personalized Medicine Care (IPMC), which integrates conventional therapies with Traditional Korean Medicine, has been applied as a complementary approach to address ESRD and its associated complications through a holistic and individualized care model. To our knowledge, this is among the first documented cases evaluating the long-term safety and efficacy of IPMC in a patient with ESRD complicated by intracerebral hemorrhage (ICH). Patient concerns: An 80-year-old male patient undergoing dialysis for ESRD since 2021 experienced a left ICH in September 2022. Poststroke, he presented with clinical challenges including uncontrolled hypertension, nutritional imbalance, and persistent constipation. Diagnoses: The patient was diagnosed with ESRD requiring regular dialysis and later suffered from a left ICH, which further complicated his clinical condition. Interventions: The patient received IPMC at Kyung Hee University Hospital, integrating conventional treatments with individualized herbal medicine and acupuncture. Herbal prescriptions were continuously adjusted in response to clinical status, laboratory markers, and interactions with concurrent medications. Outcomes: Renal function parameters stabilized during the treatment period, and clinical control of comorbidities improved. Nutritional status improved, blood pressure was effectively managed, and symptoms of constipation were resolved. Subjective enhancements in quality of life were also reported. Importantly, no hepatic or renal toxicity was observed despite the long-term administration of herbal medicines, indicating favorable safety under medical supervision. Lessons: This case demonstrates the clinical feasibility and safety of IPMC in managing ESRD patients with concurrent complications such as ICH. Long-term integration of Traditional Korean Medicine and conventional therapies may provide adjunctive clinical benefits without compromising safety. IPMC may serve as a viable supportive strategy for addressing multifactorial challenges in ESRD management. Further large-scale cohort studies are warranted to strengthen the evidence base for this integrative treatment model.

Improvements in a patient with upper limb double crush syndrome through integrative Korean medicine treatment: A case report.

Improvements in a patient with upper limb double crush syndrome through integrative Korean medicine treatment: A case report.

Rationale: Double crush syndrome (DCS) refers to multi-nerve entrapment based on the hypothesis that the distal nerve is likely to be more affected by pressure in the presence of a proximal lesion. DCS is difficult to diagnose, and thus far, few cases have been diagnosed from the perspective of DCS and reportedly treated with traditional Korean medicine. Patient concerns: The patient was a 50-year-old Korean man with DCS, hand edema, cervical radiculopathy, and upper limb paraesthesia. Diagnoses: Based on the characteristic disc symptoms and symptoms extending beyond the dermatome and myotome of the C7/T1 nerve, the patient was diagnosed with DCS. Interventions: The patient underwent 2 phases of Korean medicine treatment, including acupuncture, pharmacopuncture, Chuna manual therapy, and kinesiology taping, for 2 months. Outcomes: Significant improvement was noted in the patient’s assessments (neck pain numeric rating scale scores of 7 and 3; handshake test 50% and 90%, Spurling test (++) and (−), range of neck motion (30/20/15/15; 45/45) and (45/45/45/45; 90/90) at initial treatment and end of treatment, respectively; during phase 1, pitting edema grade scale 2 and 1 at initial treatment and end of phase 1, respectively; during phase 2, the tenderness of the lateral epicondyle of the right elbow (++) and (+−), upper limb tension test for median and radial nerve (+) and (+−) at initial treatment of phase 2 and end of phase 2, respectively). At the 3-month follow-up, physical examination findings were either further improved or maintained, and cervical spine magnetic resonance imaging also demonstrated improvement. Since oral pharmacological treatment was not utilized, no blood parameters were assessed beyond the physical examination. Lessons: Integrative Korean medicine can be considered as a treatment for DCS. More studies on the diagnosis of DCS using ultrasonography and the effectiveness of Korean medical treatment for DCS are needed in the future.

Ultrasound-Guided Pharmacopuncture for Lateral Epicondylitis Initially Misdiagnosed Due to Incomplete Common Extensor Tendon Evaluation: a case report.

Ultrasound-Guided Pharmacopuncture for Lateral Epicondylitis Initially Misdiagnosed Due to Incomplete Common Extensor Tendon Evaluation: a case report.

Management of symptoms of suspected adenomyosis uteri using herbal medicine modified Bojungikgi-tang: a case report with ultrasound monitoring.

Management of symptoms of suspected adenomyosis uteri using herbal medicine modified Bojungikgi-tang: a case report with ultrasound monitoring.

Introduction Adenomyosis is a chronic gynecological disorder characterized by the infiltration of ectopic endometrial tissue into the myometrium, affecting approximately 20–35% of women of reproductive age. Although hormonal therapy and surgery are common treatments, their side effects and impact on fertility highlight the need for alternative approaches. Recently, integrative medicine, including traditional Korean medicine, has gained attention. However, well-documented long-term case studies using objective imaging are limited. Methods A 40-year-old woman with severe adenomyosis symptoms unresponsive to conventional therapies received long-term herbal medicine based on modified Bojungikgi-tang, with regular ultrasound monitoring and clinical assessments over 12 months. Results After treatment, menstrual pain decreased from a numeric rating scale score of 7–8 to 1–2, hemoglobin normalized, and ultrasonography revealed reduced adenomyosis and improved uterine structure. The patient’s quality of life improved markedly with no adverse effects. Conclusion This case suggests that herbal medicine may be a safe and effective option for managing adenomyosis, supporting further research into integrative treatment strategies.

Persistent SARS-CoV-2 Infection in an Immunocompromised Host Treated Successfully With the Japanese Herbal Medicine, Mao-to: A Case Report.

Persistent SARS-CoV-2 Infection in an Immunocompromised Host Treated Successfully With the Japanese Herbal Medicine, Mao-to: A Case Report.

Advanced pulmonary carcinoid managed with chemoimmunotherapy and antiangiogenic agent: A case report and literature review.

Advanced pulmonary carcinoid managed with chemoimmunotherapy and antiangiogenic agent: A case report and literature review.

Case Report: Qizhi Yishen Capsule-induced bone marrow granulomas and severe myelosuppression.

Case Report: Qizhi Yishen Capsule-induced bone marrow granulomas and severe myelosuppression.

A case report of integrating Chinese and Western medicine: A new era in the treatment of late-onset Krabbe disease.

A case report of integrating Chinese and Western medicine: A new era in the treatment of late-onset Krabbe disease.

Traditional Chinese Medicine Combined With Chemotherapy for Mammary Paget's Disease With Multifocal Heterogeneous Breast Cancer: A Case Report.

Traditional Chinese Medicine Combined With Chemotherapy for Mammary Paget's Disease With Multifocal Heterogeneous Breast Cancer: A Case Report.

Successful conservative treatment of contralateral recurrent ectopic pregnancy with high β-HCG after unilateral salpingectomy: a case report.

Successful conservative treatment of contralateral recurrent ectopic pregnancy with high β-HCG after unilateral salpingectomy: a case report.